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By Liam O Connor, Francisco Martes Porto Macedo and Omar Siddique
BANGKOK, Thailand, Jan 23 2024 (IPS) – Asia and the Pacific is home to 54 per cent of the world’s urban population, who are disproportionately vulnerable to the impacts of climate change (ESCAP, 2023; IPCC, 2022). Why then, do climate action projects in cities commonly face delays in implementation?
Crucial new developments in mitigation and adaptation including: renewable energy, public transport, and nature-based solutions, are needed to safeguard the lives of billions, yet many struggle to secure sufficient funding. In fact, studies estimate that, globally, there is a $6-$12 trillion gap in annual funding for climate and resilience investment (Buchner and others, 2023).
Of the funding that does come in, only 10 per cent goes to adaptation projects (Negreiros and others, 2021), highlighting a real need to address human vulnerability in cities. So how can cities draw from greater sources of private and public investments for climate action?
Perhaps one solution is matchmaking – but not the kind you’re thinking of.
Urban-Act is an international project funded by the Government of Germany’s International Climate Initiative (IKI) with ESCAP as an implementing partner that seeks to accelerate access to urban climate finance. Urban-Act facilitates project preparation for cities, helping move their projects along the urban climate finance value chain so they can attract public or private finance.
This is followed by city climate finance matchmaking, where cities are connected with potential investors through in-person events or online platforms. This process is explored in detail in ESCAP’s 2023 working paper, Enabling Innovative Investments.
The paper highlights how project preparation and matchmaking can unlock the potential of public-private partnerships (PPPs) to bridge the climate finance gap and accelerate climate action in cities. However, several challenges must be addressed.
These challenges include:
The same paper highlights some potential solutions for providing cities with more effective support. As investors often avoid climate projects due to large upfront costs and higher perceived risks, cities can seek blended finance between private and public investors, using public grant money to prepare well-developed projects, making them attractive to private investors due to smaller ticket sizes (the amount of capital for each share) who can then fund later stage implementation (see figure 1 to visualize project value chain).
Another solution involves financial aggregation. Here matchmaking programmes can consider working with multiple cities with similar projects to better replicate interventions, and/or they could compile many small projects from one city into one portfolio, increasing funding as they leverage of economies of scale and reduced transaction costs.
Enabling Innovative Investments (2023) lists a series of recommendations for successfully employing these solutions and ultimately enabling effective city matchmaking. They range from encouraging impact assessments for learning from mistakes to engaging in investor consultation early to align projects with investor criteria.
· To achieve blended financing:
· While financial institutions should support cities by:
· To valorize financial aggregation:
· To improve the effectiveness of matchmaking efforts in the long term:
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Despite the uneven split of finances that goes towards mitigation projects, current trends show we are straying away from the 1.5°C warming target globally agreed upon at the Paris Agreement in 2015, emphasizing just how important it is that we accelerate climate finance in cities, particularly for adapting to the adverse effects of climate change that are expected to increase with time.
Projects such as Urban-Act that make use of project preparation support and city matchmaking, along with the recommendations developed in the Enabling Innovative Investments (2023) paper, can help bridge the significant investment gap for climate action, making way for more sustainable and climate resilient cities.
Liam O Connor, is Intern, Environment and Development Division, ESCAP; Francisco Martes Porto Macedo is Senior Program Associate, Cities Climate Finance Leadership Alliance, Climate Policy Initiative; Omar Siddique is Economic Affairs Officer, ESCAP.
IPS UN Bureau
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Interventions will must be tailor-made to meet the numerous
traits and motivations of customers, going past these seeking to achieve a stylised “bodybuilding appearance” or excel at sport or
even the young males trying to bulk up. Proof from the United Kingdom signifies
that there are as many AAS users over forty years of age
as there are those beneath the age of 25 years [31].
It is nicely established that AAS use just isn’t restricted to men and whereas rates amongst ladies are a lot decrease [203], the complexities
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estrogenic properties. Each of these phrases represents a different aspect of how these substances affect
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decisions. Individuals who are serious about taking anabolic
steroids should fastidiously consider each the
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The first step in treating anabolic steroid dependency is to
discontinue use and seek medical assist. For example, corticosteroids might
help individuals with bronchial asthma breathe by lowering irritation within the airways.
According to the Nationwide Institute on Drug Abuse (NIDA), continuous use of
AASs can result in problems such as tolerance, meaning a person needs larger doses to realize the same effects.
A Swedish national population-based cohort research discovered a cardiovascular morbidity and mortality rate twice as high in people who examined positive for AAS use in contrast with
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non-ischaemic heart disease charges, corresponding to cardiomyopathy and
atrial fibrillation, to be 3 times greater in those who tested optimistic for AAS use in contrast with matched controls (212).
For instance, oral pills are straightforward to use and convenient but could have a better danger of liver
toxicity, while injections can provide more secure blood ranges however could carry a risk of infections or injection web site reactions.
Following dimerization, the complicated binds to androgen response components (AREs),
which are particular promoter regions of target genes,
and this interaction impacts the transcription process [9].
In addition, fast steroid hormone activation can occur via
non-genomic pathways, which involve the interference of the steroid hormone
with the G-protein coupled receptor.
Nonetheless, including a methyl group or an ethyl group did not produce a drug with the precise properties of the father or mother compound.
The alteration of hepatic metabolism was noted to trigger strain on the liver,
and certainly all oral compounds with this C-17 addition had been discovered to trigger dose-related hepatotoxicity.
This small change was additionally found to decrease these brokers’
interplay with aromatase. [7] Subsequently, even small adjustments to those mother or father compounds cause multiple alterations within the inherent nature of AASs.
Medical interest within the useful effects of those drugs has elevated,
and ongoing research will proceed to uncover novel makes use of for these brokers and can additional outline their mechanisms of
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AASs have an essential position in musculoskeletal tissue homeostasis
and have been reported to influence the biology of
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Electrocardiogram was obtained and was important for left axis deviation but in any
other case no other vital findings (Figure 1). An echocardiogram was accomplished on a subsequent go to and
revealed gentle left ventricular hypertrophy and mildly decreased proper
ventricular function. Of necessary notice, he never had any vital
hypertension documented throughout his life. These echocardiogram findings were suggestive of direct AAS induced biventricular results.
Puberty, a critical interval for brain maturation, could be immediately influenced
by AAS, resulting in structural and mind growth changes and doubtlessly inflicting profound and lasting behavioral results (Cunningham et al., 2013).
Thus, these impacts could additionally be more pronounced in young
women, particularly adolescents, than adults (Lumia and
McGinnis, 2010). The serum concentrations of
testosterone and androstenedione differ all through female reproductive life (Huang
and Basaria, 2018).
The distinction between testosterone remedy and
steroids is a matter of intention and outcome.
The same hormones may be used in both—but if you’re
battling the signs of low T, you can relaxation assured knowing
that testosterone alternative remedy is a safe and medically-approved
remedy that may assist enhance your quality of life.
If you would possibly be struggling with low-T and are contemplating testosterone remedy to help alleviate your signs,
you don’t need to worry about your treatment being confused with performance-enhancing medicine.
By consulting with a licensed medical practitioner, you’ll be acquiring or utilizing testosterone or different androgens safely, legally, and within the pointers
of a medical prescription. Total serum testosterone must be measured periodically,
starting from the primary month after initiating therapy in patients utilizing nasal testosterone gel, and remedy ought to
terminate if whole testosterone exceeds 1050 ng/dL.
The changes made to C-17 to inhibit hepatic degradation make practically
all oral preparations hepatotoxic. The alanine aminotransferase/aspartate
aminotransferase (ALT/AST) may be seen to rise, usually
in a dose-dependent style. Ranges approaching 2-3 occasions
baseline are often set as upper limits of reference ranges when administering oral
AASs, but the risk-to-benefit ratio should be continually evaluated.
Gyno is brief for gynecomastia – male breast growth, which is a standard facet effect of some
steroid use. If an extreme quantity of estrogen conversion happens, gyno comes about, and it’s not reversible besides with surgery like liposuction. All the testosterone esters we come across are injectable, and
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